Natural ingredients such as MSM (Methylsulphonylmethane), Menthol, Camphor and a host of other ingredients, is what makes Bio-Soothe a refreshing gel. In addition, MSM offers anti-inflammatory and pain relief properties, offering deep penetrating pain relief from sore joints and other minor pains. Bio-Soothe is applied topically, cooling muscles after/ before exercise. Sufficient quantity of product should be applied 2-3 times a day to the affected area. If required, the frequency of application can be increased.